DNA芯片分析儀(dChip)(www.dchip.org)是一種用于探測(cè)級(jí)別(例如Affymetrix公司的平臺(tái))和高層次的基因表達(dá)微陣列和SNP微陣列(李和黃2001年,林等人 2004年分析的Windows軟件)。
或從不同的基因表達(dá)微陣列平臺(tái)SNP數(shù)據(jù)分析,也可以作為外部數(shù)據(jù)集進(jìn)口。在探頭水平,dChip可以顯示和正常化文件,并基于模型的方法使匯集跨多個(gè)陣列和自動(dòng)探頭的選擇來處理交叉雜交和圖像信息的污染。高級(jí)別dChip分析包括比較樣本,層次聚類,觀點(diǎn)表達(dá)以及染色體,陸和SNP單核苷酸多態(tài)性數(shù)據(jù),并復(fù)制陣列數(shù)量分析,連鎖分析。在這些功能基因的信息資料和樣品的分析結(jié)果與相關(guān)性。
DNA芯片分析軟件,似乎是兩個(gè)華人開發(fā)的軟件。
英文介紹:
DNA-Chip Analyzer (dChip) (www.dchip.org) is a Windows software package for probe-level (e.g. Affymetrix platform) and high-level analysis of gene expression microarrays and SNP microarrays (Li and Wong 2001a, Lin et al. 2004). Gene expression or SNP data from various microarray platforms can also be analyzed by importing as external dataset. At the probe level, dChip can display and normalize the CEL files, and the model-based approach allows pooling information across multiple arrays and automatic probe selection to handle cross-hybridization and image contamination. High-level analysis in dChip includes comparing samples, hierarchical clustering, view expression and SNP data along chromosome, LOH and copy number analysis of SNP arrays, and linkage analysis. In these functions the gene information and sample information are correlated with the analysis results.